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Low glycaemic index diet in patients prescribed clozapine: pilot study

Senior House Officer in Psychiatry, Murray Royal Hospital, Muirhall Road, Perth PH2 7BH

Tom White

Consultant Forensic Psychiatrist, Murray Royal Hospital, Perth PH2 7BH

AIMS AND METHOD

This study aimed to investigate the potential benefits of a low glycaemic index diet in patients with schizophrenia taking clozapine. Seven patients consented to participate in a 5-week pilot study. Measurements were taken of body weight, random blood glucose and cholesterol levels.

RESULTS

The mean weight loss per patient was 2.9 kg in 4 weeks. Random blood glucose levels reduced from a mean of 5.3 mmol/l at the beginning of the study to 4.7 mmol/l at the end.

CLINICAL IMPLICATIONS

A low glycaemic index diet may possibly reduce the substantial cardiovascular risk in patients receiving antipsychotic medication.

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